Regulating Metal In The Brain May Hold A Cure For Alzheimer’s

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Posted on 2nd February 2012 by gjohnson in Uncategorized

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In the quest to find a cure for Alzheimer’s and Parkinson’s disease, researchers are studying the impact of metals such as iron, copper and zinc on the brain, according to The Wall Street Journal.

http://online.wsj.com/article/SB10001424052970204740904577192901072611524.html

This week The Journal reported on an Australian study, published  last Sunday, that discovered that getting rid of excess iron in the brain can temper the symptoms of Alzheimer’s in tests with mice. It’s hoped that the same can be shown to be true for humans.

The presence of higher-than-normal amounts of certain metals in the brain, namely iron and copper, are found in people who have Alzheimer’s and Parkinson’s, according to The Journal. In contrast, low levels of zinc seem to negatively impact memory, and if that metal gets into the wrong parts of the brain it can cause trouble.

In the past research on Alzheimer’s has focused on markers, or certain proteins, that are found in abundance in the brain’s of those with the disease. But The Journal suggests that studying the part that metals play in the brain’s functioning could provide another option for a possible cure.

The problem with metals and the brain is that as people age, the proper level of subsances such as iron or zinc becomes unbalanced. In the case of iron, for example, that metal is important because it helps the body generate energy, according to The Journal.  But iron also creates free radicals that can damage cells in the body.

Without enough iron, a person becomes anemic. But too much iron in the brain isn’t good, and high levels of that metal has been found in the brains of people with Alzheimer’s and Parkinson’s. 

In the Australian research, aging mice who had Alzheimer’s symptoms also accumulated iron in their brains, The Journal reported. But when the mice were given a drug that got rid of the extra iron, their Alzheimer’s symptoms “reversed,” according to the story.

The article offers an interesting look at another link in the complicated path to finding a cure for dreaded Alzheimer’s.                    

The New PTSD Symptom For Vets: Anxiety And Reckless Driving

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Posted on 28th January 2012 by gjohnson in Uncategorized

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Anxiety about driving is a new symptom of post-traumatic stress disorder (PTSD) among combat veterans, according to a recent story in The New York Times.

 http://www.nytimes.com/2012/01/11/us/post-traumatic-stress-disorder-may-cause-erratic-driving.html?_r=1&ref=veteransaffairsdepartment

Unfortunately, veterans of the wars in Iraq and Afghanistan conjure up memories of their tours when they come home to the States and get behind the wheel. Driving can be dangerous under the best of circumstances, but consider what U.S. military veterans have to cope with.

Take the case outlined by The Times, that of Californian Susan Max, who served in Iraq. She didn’t want to park in any lot that didn’t have an easy escape route. At times she drive over the middle line in a road, The Times reported, because back on the war front there were sometimes bombs buried on the side of the road. 

She isn’t alone in these  experiences. Roadside bombs were a constant peril for the military who served in Iraq and Afghanistan. And that’s why doctors and psychologists are increasingly characterizing bad, dangerous driving as related to PTSD.

The problem is severe enough that insurance companies, the Pentagon and the Department of Veterans Affairs are all doing research on the relation of combat experience and aggressive driving. And they are trying to find ways to help veterans overcome their fears about driving.

In fact, Max is involved in a trial to develop techniques to allay the anxieties of vets while they’re behind the wheel. She drove around in a special car equipped with gear to measure her vital signs — such as her breathing and heart rate — along with a driving rehabilitation specialist, according to The Times.

When she started to get very nervous, he had her pull over and gave her time to relax and calm down.

Another issue regarding reckless driving and vets is that these former soldiers may be unconsciously applying the driving tactics they used in Iraq back here in the states, The Times reported, for example, that vets may run stop signs because they are used to speeding up when they come to intersections, where they were vulnerable to gunfire when in combat.    

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First Lady Unveils Coordinated Effort By Medical Schools To Train Doctors To Treat TBI, PTSD, In Vets

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Posted on 13th January 2012 by gjohnson in Uncategorized

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It looks like the Obama administration is making a real effort, on behalf of veterans and the military, to promote research and treatment of traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD).

Earlier this week First Lady Michelle Obama, during an address at Virginia Commonwealth University, announced that 130 research facilities and medical schools are joining in a coordinated effort to combat TBI and PTSD. 

http://www.whitehouse.gov/the-press-office/2012/01/11/first-lady-michelle-obama-announces-major-coordinated-effort-americas-ac

The facilities — 105 medical colleges and 25 osteopathic colleges — have committed to train students in treating brain injuries, PTSD and other mental-health issues affecting returning service members.

A press release Wednesday said that as part of  Obama and Jill Biden’s Joining Forces initiative, the Association of American Medical Colleges (AAMC) and the American Association of Colleges of Osteopathic Medicine (AACOM) had “committed to creating a new generation of doctors, medical schools, and research facilities that will make sure our heroes and their families receive the care worthy of their sacrifice.”

As part of this collaboration, the 130 schools associated with the AAMC and AACOM pledged to leverage their missions in education, research, and clinical care to train the nation’s physicians to meet the unique health care needs of the military and veterans communities. 

“I’m inspired to see our nation’s medical schools step up to address this pressing need for our veterans and military families,” the First Lady said in a statement. “By directing some of our brightest minds, our most cutting-edge research, and our finest teaching institutions toward our military families, they’re ensuring that those who have served our country receive the first-rate care that they have earned.”

The AAMC and AACOM are committing to improve the education in their medical schools, the research in their laboratories, and the clinical care in their hospitals to better address the health issues that military families face, according to the press release. Let’s hope that’s true. 

Specifically, these organizations are committing to:

• Train their medical students as well as their current physicians, faculty, and staff to better diagnose and treat veterans and military families
• Develop new research and clinical trials on PTSD and TBI to better understand and treat those conditions
• Share their information and best practices with one another through a collaborative web forum created by the AAMC
• Continue to work with the VA and the Department of Defense to make sure that everyone is providing the best care available.

“Because of our integrated missions in education, clinical care, and research, America’s medical schools are uniquely positioned to take a leadership role in this important effort,” said Dr. Darrell Kirch, president and CEO of the Association of American Medical Colleges.

 “Medical schools have long recognized the sacrifice and commitment of our military, veterans and their families,” he said. ” The relationship between the Department of Veterans Affairs medical centers and academic medicine dates back to the end of World War II and serves as a model for successful partnerships between public and private institutions.  Our work with the White House on Joining Forces is a natural extension of our efforts in this area and renews our commitment to the wellness of our nation’s military.”

Dr. Stephen Shannon, president and CEO, American Association of Colleges of Osteopathic Medicine, also had a statement.

“A central component of the White House Joining Forces Initiative is wellness, and I am pleased to announce AACOM’s participation in a new Joining Forces effort that could have a significant impact on the health and well-being of our nation’s veterans,” he said. 

Examples of universities stepping up to provide for veterans and their families include:

• Virginia Commonwealth University, where they’re leading a groundbreaking project to provide resources and training to health care providers, volunteers, and community members throughout Virginia who can help ease the transition home for veterans with TBI and PTSD.
• The University of Pittsburgh, where researchers are developing a new imaging tool that allows the visualization of the wiring of the brain in vivid high definition, which could lead to new breakthroughs in the diagnosis of TBI.
• The University of South Florida, where they are working with the Department of Defense and the VA to create a first-of-its-kind Center for Veterans Reintegration, which will mean a single, cohesive research, treatment and education facility for veterans and families.

Obama and  Biden created Joining Forces to bring Americans together to recognize, honor and take action to support veterans and military families as they serve our country and throughout their lives. The initiative aims to educate, challenge, and spark action from all sectors of society to ensure veterans and military families have the support they have earned.

The initiative focuses on key priority areas – employment, education, and wellness while raising awareness about the service, sacrifice, and needs of America’s veterans and military families.

 More information is available at: www.JoiningForces.gov.

Here is a list of the 130 universities and colleges participating in the new  program:

• University of Alabama School of Medicine
• University of South Alabama College of Medicine
• University of Arkansas for Medical Sciences College of Medicine
• Arizona College of Osteopathic Medicine of Midwestern University
• AT Still University School of Osteopathic Medicine of Arizona
• University of Arizona College of Medicine
• Loma Linda University
• Keck School of Medicine of the University of Southern California
• Touro University California College of Osteopathic Medicine
• Stanford University School of Medicine
• UC Davis Health System
• University of California, Irvine School of Medicine
• David Geffen School of Medicine at UCLA
• Western University of Health Sciences College of Osteopathic Medicine of the Pacific
• Rocky Vista University College of Osteopathic Medicine
• University of Colorado School of Medicine
• Yale School of Medicine
• Georgetown University School of Medicine
• George Washington University School of Medicine and Health Sciences
• Howard University College of Medicine
• Florida State University College of Medicine
• Herbert Wertheim College of Medicine Florida International University
• Nova Southeastern University College os Osteopathic Medicine
• University of Florida College of Medicine
• USF Health Morsani College of Medicine
• Emory University School of Medicine
• Medical College of Georgia at Georgia Health Sciences University
• Mercer University School of Medicine
• Morehouse School of Medicine
• University of Hawaii at Manoa, John A. Burns School of Medicine
• Des Moines University College of Osteopathic Medicine
• University of Iowa Carver College of Medicine
• Chicago College of Osteopathic Medicine of Midwestern University
• Loyola University Chicago Stritch School of Medicine
• Rush University Medical Center, Chicago
• Southern Illinois University School of Medicine
• The Chicago Medical School in conjunction with the Lovell Federal Health Care Center
• University of Chicago Pritzker School of Medicine
• University of Illinois College of Medicine
• Indiana University
• University of Kansas Medical Center
• University of Kentucky College of Medicine
• University of Pikeville Kentucky College of Osteopathic Medicine
• Louisiana State University School of Medicine in New Orleans
• Tulane University School of Medicine
• Boston University School of Medicine
• Harvard Medical School
• Tufts University School of Medicine
• University of Massachusetts Medical School
• Johns Hopkins University School of Medicine
• Uniformed Services University of the Health Science’s F. Edward Hebert School of Medicine
• University of Maryland School of Medicine
• University of New England College of Osteopathic Medicine
• Michigan State University College of Human Medicine
• Michigan State University College of Osteopathic Medicine
• University of Michigan Medical School
• Wayne State University School of Medicine
• University of Minnesota Medical School
• Kansas City University of Medicine and Biosciences College of Osteopathic Medicine
• Kirksville College of Osteopathic Medicine AT Still University
• Saint Louis University
• University of Missouri-Columbia School of Medicine
• University of Missouri – Kansas City School of Medicine
• Washington University in St. Louis School of Medicine
• University of Mississippi School of Medicine
• Creighton University School of Medicine
• University of Nebraska Medical Center College of Medicine
• The Brody School of Medicine at East Carolina University
• Wake Forest School of Medicine
• University of North Carolina at Chapel Hill School of Medicine
• University of North Dakota School of Medicine and Health Sciences
• Dartmouth Medical School
• Cooper Medical School of Rowan University.
• University of Medicine and Dentistry of New Jersey – New Jersey Medical School
• University of Medicine and Dentistry of New Jersey – Robert Wood Johnson Medical School
• University of Medicine and Dentistry of New Jersey – School of Osteopathic Medicine
• University of New Mexico School of Medicine
• University of Nevada School of Medicine
• Hofstra North Shore – LIJ School of Medicine
• New York Institute of Technology New York College of Osteopathic Medicine
• State University of New York Upstate Medical University
• Touro University College of Osteopathic Medicine
• University at Buffalo State University of New York School of Medicine & Biomedical Sciences
• Case Western Reserve University School of Medicine
• The Ohio State University
• Ohio University College of Osteopathic Medicine
• University of Cincinnati College of Medicine
• University of Toledo College of Medicine
• Wright State University Boonshoft School of Medicine
• Oklahoma State University College of Osteopathic Medicine
• University of Oklahoma College of Medicine
• Oregon Health & Science University School of Medicine
• Pacific Northwest University of Health Science College of Osteopathic Medicine
• Commonwealth Medical College
• Drexel University College of Medicine
• Jefferson Medical College of Thomas Jefferson University
• Lake Erie College of Osteopathic Medicine
• Perelman School of Medicine at the University of Pennsylvania
• Penn State University College of Medicine
• Philadelphia College of Osteopathic Medicine
• Temple University School of Medicine
• University of Pittsburgh School of Medicine
• Universidad Central del Caribe School of Medicine
• Ponce School of Medicine and Health Sciences
• Medical University of South Carolina College of Medicine
• University of South Carolina School of Medicine
• University of South Carolina School of Medicine, Greenville
• University of South Dakota Sanford School of Medicine
• Lincoln Memorial University DeBusk College of Osteopathic Medicine
• Meharry Medical College
• Vanderbilt University School of Medicine
• Baylor College of Medicine
• The Texas A & M Health Science Center College of Medicine
• Texas Tech University Health Sciences Center School of Medicine
• Texas Tech University Health Sciences Center School of Medicine Paul L. Foster School of Medicine
• The University of North Texas Health Science Center Texas College of Osteopathic Medicine
• The University of Texas School of Medicine at San Antonio
• University of Texas Medical School at Houston
• University of Utah School of Medicine
• Eastern Virginia Medical School
• University of Virginia School of Medicine
• Virginia Commonwealth University School of Medicine
• Virginia Tech Carilion School of Medicine
• Edward Via College of Osteopathic Medicine
• University of Washington School of Medicine
• Medical College of Wisconsin
• University of Wisconsin School of Medicine and Public Health
• The Joan C. Edwards School of Medicine at Marshall University
• West Virginia School of Osteopathic Medicine
• West Virginia University School of Medicine

New Jersey Prepares For First Season Of Skiing, Snowboarding Helmet Law

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Posted on 13th December 2011 by gjohnson in Uncategorized

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New Jersey retailers in ski areas are busy stocking up on helmets,  all  because of a new state law.

http://www.lehighvalleylive.com/phillipsburg/index.ssf/2011/12/new_jersey_ski_helmet_law_take.html

The Garden State this spring, in April, became the first state to pass legislation that requires juvenile skiers and snowboarders to wear helmets, beginning this season. Those who are 17 and younger have to wear the safety gear.

The penalities for violation of the new law fall on the parents or guardians of the kids. They will have to pay a $25 fine the first time their child doesn’t wear a helmet while skiing or snowboarding, and $100 for each additional violation, according to The Express-Times. 

So right now ski resorts in areas such as Sussex County, N.J., and the stores that surround them, are loading up their inventories of helmets. One shop, Cannonball Winter Sports, has stocked up with 150 helmets, The Express-Times reported.

The ski resort Mountain Creek has quadrupled it stock of rentable helmets since 2009, to 2,000 from 500, according to The Express-Times. The resort rents the helmets at $10 a pop.

Is it worth the trouble? Some research says it is. A study by the University of Calgary found that a helmet cuts the chance of a head injury by about 35 percent for skiers and snowboarders. 

The new helmet law is well-intentioned, but appears difficult to enforce, according to The Express-Times. Ski resorts are not empowered to enforce the law, only local police and and New Jersey State troopers are. But when is the last time you saw any of them on a ski slope?  

Stroke Victim’s Family Faces Financial Ruin Due To Medical Bills

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Posted on 25th November 2011 by gjohnson in Uncategorized

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Brain injuries no only take a horrific physical and emotional toll on patients and their families, they can also take a financial toll. 

Such is the case with the Granelli family of Stanhope, N.J., who are in financial ruin after Karen Granelli, 55, suffered a burst aneurism and stroke about three years ago. Her story was chronicled by Star-Ledger columnist Bob Braun on Monday, in an article with the headline, “A terrible affliction, an unbearable debt.”

http://blog.nj.com/njv_bob_braun/2011/11/braun_plight_of_stanhope_famil.html

Karen and her husband Joesph had been doing well, essentially untouched by the recession, prior to her illness. She was a rehabilitation counselor. He was a quality assurance engineer who moonlighted as an appliance salesman, according to Braun. Their daughter Sarah was attending Seton Hall University.

But then Karen had a stroke, which ended up paralyzing her.

In the wake of that life-altering experience, the Granellis are losing everything they worked so hard to get because of their staggering medical bills.

The couple is in bankruptcy and their home is in foreclosure, according to Braun. Their daughter had to drop out of college. And the Granellis are responsible for medical bills “for more than $650,000 not covered by insurance or limited by the bankruptcy filing,” Braun wrote. 

The medical bills are for several weeks that Karen was hospitalized. As Braun points out, Joseph Granelli’s $1 million medical insurance’s lifetime cap was reached quite quickly. This is the kind of problem anyone with a brain injury could face.

“The Granellis aren’t the only people in trouble because of their medical bills, but their story is remarkable because they hit the bottom so  fast — despite spending their lives doing everything right,” Braun wrote.

And that’s wrong.

  

Justice Requires the Brain Injury Voice to Be Heard

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Posted on 8th August 2011 by gjohnson in Uncategorized

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I started this blog because I felt that as an advocate, sometimes I needed to comment on American politics, to advance my agenda of finding justice for my clients and others with brain injury. Justice to a significant degree means due process of law, which can be largely reduced to making sure that your full story is heard.

For brain injury survivors, injustice too often happens because their story is never heard by those making judgments about their condition and treatment. And far too much of the reason that the story is never heard is that the doctors don’t know what they should be listening for. Diagnosing and understanding brain injury disability is about the application of clinical wisdom to the individualized facts of the injury and deficits. The only way that a professional can gain that wisdom is by listening to the TBI Voice.

I launched http://tbivoices.com to tell the TBI story. Through the TBI Voices project, we are providing an internet archive of brain injury voices. The goal is to create a comprehensive treatment of the subjective aspects of TBI. Each story includes the voice of the survivor, the context injury and the nature of the treatment and disability. If this archive can become a chorus of brain injury voices, it may influence the diagnosis and treatment of TBI in a way that current research – that is based upon objective measurement of an injury that is exceedingly hard to measure and almost impossible to quantify – cannot.

To date, we have provided a platform for fourteen brain injured people to tell their story. But unlike survivor stories online, each of these stories has a similar structure, is a detailed treatment of the TBI, the severity of the injury, the rehabilitation and recovery process and current ability. http://tbivoices.com is in some way the flipside of the http://www.waiting.com/waitingbridge.html of waiting.com as it is a page filled with hope, a page filled with comebacks, a page of belief in miracles.

Here is the Table of Contents of stories on http://tbivoices.com Each day we post add part of a story on http://tbivoices.com/blog and every 15 days or so begin another story. What is also unique about http://tbivoices.com is that you can hear the survivor’s voice as the  full interviews are posted on Youtube at http://youtube.com/tbivoices

I hope that through this webpage, we can provide a place where the TBI community can be heard.

Attorney Gordon Johnson

Bronx Teen Continues Recovery From Gunshot Wound In The Brain

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Posted on 15th November 2010 by gjohnson in Uncategorized

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 It’s great to read a story about a traumatic brain injury victim who makes a comeback beyond all expectations. And that is certainly the case with Vada Vasquez.

The New York Post Monday printed a photo of Vasquez as she lay on a sidewalk in the Bronx, shot in the head during a gang war last year, her eyes open, bleeding onto the concrete. She was 15 then, on Nov. 16, 2009, when she was hit with a bullet meant for another person. She was an innocent victim caught in the middle of a gangbang battle.

  http://www.nypost.com/p/news/local/bronx/miracle_teen_hard_road_back_XaPXO7qhHr75J9Dg43jweI

The Post did a full update on Vasquez Monday, a story headlined “Miracle Teen’s Hard Road Back.”

After she was shot, doctors operated on Vasquez to take out the bullet that had hit the left temporal lobe of her brain, the part of the mind that controls speech, according to The Post.  The teen was in a coma for several days before waking up with no memory of the shooting.

Vasquez spent last Thanksgiving in rehab at Mount Sinai Medical Center. She went through painstaking speech therapy there, according to The Post, initially struggling unsuccessfully to say the words “love” and “hi.” What was frustrating was that Vasquez knew she had been able to say those words before.

The young woman was home for Christmas, and she was still having trouble speaking. At that time, she had to wear a helmet because she was awaiting surgery to reconstruct her skull.

She had that surgery in February, and has made great strides in her rehab, all described by The Post. 

But Vasquez is not out of the woods. She still gets horrible headaches — and nightmares. But she’s upbeat, and happy to be alive to have celebrated her 16th birthday earlier this month at the local Great Adventure.

   

New York Mayor Bloomberg’s Daughter Suffers Concussion After Horse Jump

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Posted on 8th November 2010 by gjohnson in Uncategorized

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New York City Mayor Michael Bloomberg’s younger daughter was set to undergo additional tests Monday after sustaining a concussion during a fall while performing at an equestrian tournament.

http://cityroom.blogs.nytimes.com/2010/11/08/bloomberg-says-daughter-is-recovering-after-fall/?scp=9&sq=mayor%20bloomberg&st=cse

Georgina Bloomberg, 27,  was briefly unconscious and fractured several vertebrae Friday when she fell off her mount during the competition in Syracsue, N.Y.

She was riding a horse, named Radio C ity, over a fence when, in the middle of the animal’s jump, its saddle came loose and Bloomberg fell off. She did walk out of the Oncenter War Memorial Arena on her own.  

The daughter was slated to have an MRI Monday. 

 

 

 

Hypertonic Fluids Don’t Help Brain Injury Victims, Study Finds

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Posted on 6th October 2010 by gjohnson in Uncategorized

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 Here’s another setback in the emergency treatment of brain injury.

A study has found that hypertonic fluid, a concentrated saline solution that paramedics administer intravenously to  head trauma patients, doesn’t help improve the patients’ chances of survival or their later brain function, according to a story in The Wall Street Journal Wednesday.

http://online.wsj.com/article/SB10001424052748703298504575534362216876780.html?mod=ITP_pageone_1

 The story, headlined “Saline Fluid Fails in Brain Therapy,” reports that a study released this week found that hypertonic fluid is not effective in the treatment of blunt traumatic brain injuries. That makes the saline solution the latest treatment, following anti-oxidants and intravenous magnesium, to flunk tests gauging their ability to help brain-trauma victims.

It has been believed that hypertonic fluid improves the blood flow in the brain while also decreasing intercranial pressure, and both those effects aid brain injury victims.  

The hypertonic fluid study, published in this week’s Journal of the American Medical Association ( JAMA), involved 1,282 patients treated by paramedics. The patients were either given regular saline solution or the hypertonic variety, which has eight times as much salt as the regular saline, according to The Journal.      

http://jama.ama-assn.org/cgi/content/abstract/304/13/1455

 The study’s authors, who included University of Washington surgery professor Eileen Bulger, said they couldn’t see any improvement in the six-month neurological outcome of the patients who received the hypertonic solution, according to The Journal. 

The study’s authors also wrote that there was “no compelling reason” to use “hypertonic fluid resuscitation for TBI in the out-of-hospital setting.”

The Journal Wednesday also noted that the U.S. Department of Defense has awarded $26.3 million to Banyan Biomarkers Inc. of Alachua, Fla. The military wants Banyan to devise a blood test to determine “the presence and severity of brain injury,” the newspaper reported. Biomarkers are proteins that an injured brain produces.

In the combat arena, the biomarker test would let the military immediately identify who has suffered brain injury in a bomb blast, and get them off the battlefield for treatment.      

  

Mother Of College Football Player Who Committed Suicide, And Had Brain Disease, To Testify At Congressional Hearing

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Posted on 18th September 2010 by gjohnson in Uncategorized

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This Thursday’s Congressional hearing on youth sports concussions will have an especially interesting witness: the mother of the University of Pennsylvania football player who committed suicide, and was found to be suffering from the same brain disease nearly two dozen pro football players had.

The Rev. Kathy Brearley, mother of Owen Thomas, will testify at the hearing before the House Education and Labor Committee, The New York Times reported Saturday. Next week’s hearing will be the eighth one on athletes and concussions since October. 

http://www.nytimes.com/2010/09/18/sports/18concussions.html?scp=3&sq=Owen%20thomas&st=cse

Owen Thomas’ life and death raises troubling new questions about brain injury and football. The 21-year-old took his own life in April, and tests were done on his brain tissue. The news was released last week that Thomas had begun to develop chronic traumatic encephalopathy, a brain disease linked to repeated brain injury that often leads to depression and impulse control issues. 

The discovery was disturbing in that Thomas had never been diagnosed with a concussion, was still young at 21 and was only playing college football, not in the NFL.    

 The Congressional committee is weighing a law that would mandate that all public schools implement a concussion safety plan for all sports, offer special education for the injured who still have symptoms, and remove athletes immediately from practice and games if they are suspected of having a concussion, according to The Times.

The Times also cited particularly grim statistics from the National Center for Catastrophic Sport Injury Research at the University of North Carolina: Roughly 32 high school and youth football players died or made incomplete recovery from head injuries from 2006 to 2009, double the number from the prior four-year period. 

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